High-resolution quantitative magnetization transfer imaging of post-mortem marmoset brain
نویسندگان
چکیده
Purpose. Quantitative magnetization transfer imaging (qMTI) provides information on otherwise MR-invisible macromolecules via cross relaxation or proton exchange with water molecules. In cerebral white matter (WM), qMT parameters are assumed to be related to myelination and have been used as markers of WM pathology [1]. This is particularly true for the macromolecular pool-size fraction, M0b. In this abstract, we investigate whether high-resolution (200 μm isotropic ) qMTI at 3 T can visualize indicators of myelination well in a post-mortem marmoset brain. We compare our findings with T1 mapping in the same brain at 7 T, since T1-weighted imaging is more commonly used for visualizing neuroanatomy.
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